Recombinant RSV A Glycoprotein G, mFc-tagged
Specification
Related Products
| Cat#: |
RES-552 |
| Product Name: |
Recombinant RSV A Glycoprotein G, mFc-tagged |
| Description: |
This Human RSV (A) glycoprotein G comprises amino acids 67-298 of the major glycoprotein of RSV. It contains a C-terminal mouse IgG2a Fc-tag with a 15 AA glycine-serine linker. |
| Gene: |
Glycoprotein G |
| Species: |
RSV |
| Source: |
HEK293 |
| Synonyms: |
Respiratory Syncytial Virus A Glycoprotein G |
| Formulation: |
DPBS pH7.4, sterile filtered. |
| Concentration: |
0.89 mg/mL |
| Purity: |
Greater than 95% purity |
| Storage: |
Short Term Storage: +2 centigrade to +8 centigrade
Long Term Storage: -80 centigrade |
| Notes: |
This product is intended for research and manufacturing uses only. It is not a diagnostic device. The user assumes all responsibility for care, custody and control of the material, including its disposal, in accordance with all regulations. |
| Tags: |
C-terminal mouse IgG2a Fc |
| Freezing: |
Can be frozen, but avoid multiple freeze/thaw cycles. |
| Sequence Strain: |
Long |
| Background: |
Human Respiratory Syncytial Virus (RSV) is a single-stranded RNA virus, which was first isolated in 1956 from a laboratory chimpanzee with a respiratory illness and was later discovered to be of human origin. RSV consists of two antigenic subtypes, A and B. Subtype B tend to produce asymptomatic infections, whilst the more severe illnesses which predominate during outbreaks are associated with subtype A strains. RSV is the leading cause of lower respiratory tract infections, including pneumonia and bronchiolitis in young infants. Approximately two thirds of infants are infected with RSV within their first year and 90% have been infected by the age of 2. It may cause mortality or morbidity in the elderly as well as immunodeficient individuals. It is the most common pathogen leading to hospitalization in young children up to the age of 5.
The virion of Respiratory Syncytial Virus (RSV) contains three surface glycoproteins, the attachment protein G, fusion protein F, and the small hydrophobic SH protein. Glycoprotein G is a type II transmembrane glycoprotein and is the major RSV attachment protein. It contains a single hydrophobic region which serves as a signal peptide and also as a membrane anchor. The structure and function of RSV glycoproteins has been reviewed by McClellan et al (2013). |
For research use only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
