After obtaining target antibodies through various methods, researchers use the reaction principle of cascade amplification to label some substances that are easy to measure and highly sensitive to specific antigens or antibody molecules, such as HRP, FITC, biotin, etc. Finally, the enhanced amplification effect of these markers is used to display or quantify the nature and content of the antigen or antibody in the reaction system. The applications of antibody conjugation technology mainly include in vitro diagnosis (IVD) of tumor markers, pathogenic microorganisms, and immune diseases. Antibody drugs prepared by this technology that target specific immune molecules are used for immune disease detection.
Figure 1. The site-specific antibody conjugation using payloads other than synthetic cytotoxins. (Zhou Q, 2023)
Creative BioMart is committed to providing direct-conjugated antibodies with specificity and consistency, allowing you to seamlessly transition from R&D to manufacturing and preclinical development.
Core Technologies of Our Antibody Conjugation Service
Antibodies are usually prepared using hybridoma technology or genetic engineering. These antibodies with high affinity and specificity can effectively bind to the target antigen.
Customize exclusive antibodies according to customer needs and combine them with specific tags for analysis.
A variety of labels are available, including TR-FRET, HTS, western blot, etc.
Many types of antibody options meet different customer needs.
High purity, ultra-low endotoxin levels, and no other impurities.
Creative BioMart focuses on the research and development of IVD proteins, and its business covers custom synthesis of peptides, antibody labeling, and development of custom coupling kits to meet the different application needs of customers.
Types of Antibody Labels We Offer
Enzyme label
Biotin label
Colloidal gold label
Fluorescent label
Alexa Fluor
ATTO series fluorescent dyes
Antibody Conjugation Service Items
Creative BioMart can provide customers with services such as antibody labeling, the development of custom coupling kits, and protein detection customization services to meet different needs.
Service Range
Service Content
Solution Customization
Consultation to determine optimal dyes and coupling chemistries
Select the desired label
Antibody Selection
Buy antibodies directly
Customized antibodies
Binding and Purification
For the binding reaction, each antibody is spiked with a small amount of biotin or synthetic dye
Remove unbound dye or biotin by SEC-FPLC or desalting
Sterile filtered
QC
Measure antibody concentration and fluorescence to protein (F/P) ratio
Fluorimetry or size exclusion chromatography
Certificate of Analysis (CoA)
Reasons to Choose Us
The professional technical team will customize products according to customer needs.
With rich experience in antibody production and conjugation, we can ensure the quality of our products.
High success rate and low risk.
Products can be successfully delivered in a short time, saving time.
Additional services include endotoxin removal, murine pathogen screening, and cell line conservation.
Creative BioMart focuses on IVD proteins, we can provide services such as small-scale and large-scale protein production for IVD and the development of recombinant proteins, antibodies, and bioanalytical tests, aiming to provide global pharmaceutical companies and life science research institutions with high-quality IVD protein service. If you are interested in our services, please contact us and we will provide you with detailed assistance.
Figure 1. The site-specific antibody conjugation using payloads other than synthetic cytotoxins. (Zhou Q, 2023)
