Hepatitis C is a viral hepatitis caused by hepatitis C virus (HCV) infection. It is mainly transmitted through blood. Hepatitis C is a global epidemic and can lead to chronic inflammation and necrosis of the liver, and even develop into Liver cirrhosis or hepatocellular carcinoma are extremely harmful to human health and life and have become serious social and public health problems. HCV infection is primarily determined clinically by measuring hepatitis C core antigens (HCV-cAgs) and hepatitis C antibodies (HCV-Abs).
Figure 1. HCV-related mechanisms of carcinogenesis: from HCV infection to HCC. (Vescovo T, et al., 2016)
In vitro diagnostic (IVD) methods for HCV mainly rely on biochemistry and molecular biology techniques.
Main Methods of IVD for Hepatitis C Virus
HCV antibody and antigen test. Antibody testing can determine whether patients have been infected with HCV by detecting HCV-Ab or HCV-cAg levels in the serum.
HCV RNA testing. HCV genetic material, HCV-RNA, can be detected in blood by RNA testing for HCV infection.
Polymerase chain reaction (PCR) technology is used to amplify and detect the HCV gene sequence using specific probes.
Creative BioMart can provide high-quality recombinant HCV core proteins used for IVD, including ELISA, lateral flow assays, western blots, and other immunoassays.
High sensitivity, high specificity, and high purity.
It is widely used and suitable for downstream immunological experiments.
Easy to store and transport, conducive to large-scale production and use of vaccines.
Outstanding success rate and fast development speed.
Our Outstanding Advantages
IVD proteins can be used to test for a variety of diseases and conditions, making them valuable tools for diagnosing and monitoring health.
Guarantee high performance, high reliability, and high consistency of protein quality, leading the industry.
A complete IVD protein platform can provide customized services to meet different scientific research needs.
High-quality service, high-level experiments, and reliable analysis.
In addition, Creative BioMart also offers a series of viral proteins and protein-related services to provide customers with high-quality, low-cost active recombinant proteins to meet different needs and assist in preclinical drug development.
Creative BioMart offers a series of highly efficient and reliable IVD proteins, providing strong support for medical research and preclinical diagnosis. At the same time, we provide more flexible and personalized protein services that are used in IVD reagents, drug development, biotechnology research and production, and other fields. Please contact us for answers if you are interested in our products or services.
Reference
Vescovo T, Refolo G, Vitagliano G, et al. (2016). Molecular mechanisms of hepatitis C virus–induced hepatocellular carcinoma[J]. Clinical Microbiology and Infection. 22(10): 853-861.
Figure 1. HCV-related mechanisms of carcinogenesis: from HCV infection to HCC. (Vescovo T, et al., 2016)
