Salmonella is a common foodborne pathogen, a gram-negative bacillus that mainly infects the gastrointestinal tract of patients. Salmonella infection can occur when eating certain contaminated foods, including raw poultry, eggs, and beef, or handling pets, especially birds and reptiles. The main symptoms that patients often experience after infection are diarrhea, fever, nausea, and vomiting. Currently, doctors rely on laboratory testing of patient stool and blood samples to diagnose salmonella infections in vitro. Generally required examinations include blood routine, bacteriological examination, and serum agglutination test.
Figure 1. Key molecular mechanisms underlying the pathogenesis of salmonellosis. (Knodler L A, et al., 2019)
Main Steps of IVD for Salmonella
Serum agglutination test (IHA). An agglutination test is performed using the patient's serum and bacterial antigens made from known bacterial species. If the agglutination titer increases abnormally, the patient can be diagnosed as infected.
Blood examination. The total number of white blood cells is mostly normal but increases significantly when there are focal purulent lesions.
Fecal examination. Some stools contain mucus and blood, and some may show increased neutrophils under the microscope, which are characteristics of salmonella enteritis and other large-scale damage to the intestinal mucosa.
Bacteriological examination. Pathogenic bacteria were detected from the patient's blood, pus, pleural effusion, cerebral effusion, joint effusion, etc.
Creative BioMart provides high-quality recombinant Salmonella H antigen protein used for IVD, including ELISA, lateral flow assays, western blots, and other immunoassays.
Highlights of Our Products
High sensitivity, high specificity, and high purity.
It is widely used and suitable for downstream immunological experiments.
Easy to store and transport, conducive to large-scale production and use of vaccines.
Outstanding success rate and fast development speed.
Our Outstanding Advantages
IVD proteins can be used to test for a variety of diseases and conditions, making them valuable tools for diagnosing and monitoring health.
Guarantee high performance, high reliability, and high consistency of protein quality, leading the industry.
A complete IVD protein platform can provide customized services to meet different scientific research needs.
High-quality service, high-level experiments, and reliable analysis.
In addition, Creative BioMart also offers a series of viral proteins and protein-related services to provide customers with high-quality, low-cost active recombinant proteins to meet different needs and assist in preclinical drug development.
Creative BioMart offers a series of highly efficient and reliable IVD proteins, providing strong support for medical research and preclinical diagnosis. At the same time, we provide more flexible and personalized protein services that are used in IVD reagents, drug development, biotechnology research and production, and other fields. Please contact us for answers if you are interested in our products or services.
Reference
Knodler L A, Elfenbein J R. (2019). Salmonella enterica[J]. Trends in microbiology. 27(11): 964-965.
Figure 1. Key molecular mechanisms underlying the pathogenesis of salmonellosis. (Knodler L A, et al., 2019)
