Phleum pratense is a common lawn grass whose pollen is the main allergen confirmed to cause grass fever. Phleum pratense pollen allergen is a plant-based allergen that mainly enters the human body through pollen particles in the air, thereby stimulating the body's immune system to produce allergic reactions, such as dermatitis, anaphylactic shock, asthma, and other symptoms. Current research shows that Phleum pratense pollen allergens mainly include Phl p 1, Phl p 2, Phl p 5, Phl p 7, and Phl p 12. In vitro diagnosis (IVD) of grass pollen allergy is usually based on the detection of IgE antibodies in serum.
Main Steps of IVD for Phleum pratense Allergy
Immunological Test
Detection of IgE levels in serum, including total IgE determination and specific IgE determination. These assays can detect a patient's specific immune response to Phleum pratense pollen.
Skin Prick and Intradermal Test
In these tests, pollen extract is pierced or injected into the skin and the skin's reaction is observed to determine whether an allergic reaction occurs.
Biosensor Technology
This technology can detect the electrical signal when pollen allergens combine with IgE antibodies, thereby quickly and accurately detecting whether the patient is allergic to pollen.
Creative BioMart provides high-quality recombinant Phleum pratense allergen proteins used for IVD, including ELISA, lateral flow assay, western blot, and other immunoassays.
High purity for compliance with experiment standards.
High specificity. The molecular structure and biological activity of recombinant allergens are similar to natural allergens and can effectively stimulate immune responses in allergic patients.
Easy to scale up production. A large number of specific proteins can be obtained through process amplification, without being limited by the content of natural extracts and materials.
Our Outstanding Advantages
Provide a series of recombinant allergen proteins for IVD applications, including food, pollen, and mite allergens.
Strong technical team, advanced scientific research equipment, and technology that can provide high-quality services.
A rich variety of IVD products to meet the different needs of customers and provide customers with comprehensive scientific research support.
Ensure high standards of service quality and delivery of timely and accurate IVD services to customers, with a focus on providing the best possible scientific research experience.
In addition, Creative BioMart also offers a series of allergen proteins and protein-related services to provide customers with high-quality, low-cost active recombinant proteins to meet different needs and assist in preclinical drug development.
Creative BioMart is dedicated to researching and developing IVD proteins whilst providing superior products for medical research and preclinical diagnoses. Our extensive protein services apply to IVD reagent synthesis, drug development, biotechnology research, and other fields. Should our products or services pique your interest, please do not hesitate to contact us for more information.
Reference
Tripodi S, Frediani T, Lucarelli S, et al. (2012). Molecular profiles of IgE to Phleum pratense in children with grass pollen allergy: implications for specific immunotherapy[J]. Journal of allergy and clinical immunology. 129(3): 834-839. e8.
