Influenza B virus is an RNA virus that causes seasonal influenza and mainly infects humans and a few mammals. After infection, patients will develop symptoms such as high fever, cough, and breathing, as well as severe cases may be accompanied by heart and kidney failure. Compared with the influenza A virus, the symptoms, testing, and treatment are similar, but the severe disease and fatality rates are lower. Due to the characteristics of high sensitivity, specificity, and short time consumption, molecular biology diagnostic technology has become an indispensable method in the in vitro diagnosis (IVD) of influenza B virus.
Figure 1. Influenza B proteins, their function, and antiviral targets. (Zaraket H, et al., 2021)
Main Steps of IVD for Influenza B Virus
Virus culture. Virus detection by cytopathic effect, hemagglutinin assay, or fluorescent antibody staining.
Viral antigen testing. The patient's nasopharyngeal secretions were collected for viral antigen detection. If the test result is positive, it indicates that the patient is infected with the influenza B virus.
Viral nucleic acid detection. Samples such as nasal swabs, throat swabs, nasopharyngeal swabs, tracheal extracts, or sputum from patients are collected for PCR, RT-PCR, and LAMP.
Microarray chip technology.
Creative BioMart provides high-quality recombinant influenza B nucleoprotein used for IVD, including ELISA, lateral flow assays, western blots, and other immunoassays.
Highlights of Our Products
High sensitivity, high specificity, and high purity.
It is widely used and suitable for downstream immunological experiments.
Easy to store and transport, conducive to large-scale production and use of vaccines.
Outstanding success rate and fast development speed.
Our Outstanding Advantages
IVD proteins can be used to test for a variety of diseases and conditions, making them valuable tools for diagnosing and monitoring health.
Guarantee high performance, high reliability, and high consistency of protein quality, leading the industry.
A complete IVD protein platform can provide customized services to meet different scientific research needs.
High-quality service, high-level experiments, and reliable analysis.
In addition, Creative BioMart also offers a series of viral proteins and protein-related services to provide customers with high-quality, low-cost active recombinant proteins to meet different needs and assist in preclinical drug development.
Creative BioMart offers a series of highly efficient and reliable IVD proteins, providing strong support for medical research and preclinical diagnosis. At the same time, we provide more flexible and personalized protein services that are used in IVD reagents, drug development, biotechnology research and production, and other fields. Please contact us for answers if you are interested in our products or services.
Reference
Zaraket H, Hurt A C, Clinch B, et al. (2021). Burden of influenza B virus infection and considerations for clinical management[J]. Antiviral Research. 185: 104970.
Figure 1. Influenza B proteins, their function, and antiviral targets. (Zaraket H, et al., 2021)
