In the Mediterranean region, where olive trees are widely planted, olive hay fever has become an important health problem. Olive pollen, an immunoglobulin E (IgE)-mediated allergen, is one of the most important causes of respiratory allergies due to the large amounts of pollen released by olive trees into the atmosphere. Currently, in vitro diagnostics (IVD) identifies the most clinically relevant sensitizing allergen for olive pollen allergy, Ole e 1, by detecting specific IgE antibodies in patients using specific reagents or serological methods.
Main Steps of IVD for Olea europaea Allergy
Immunological Test
The main methods are ELISA, immunoblotting, radio allergen absorption test (RAST), etc. Detect IgE antibodies or cytokines in serum, focusing on total IgE determination and specific IgE determination. The amount of specific IgE antibodies can help identify allergens.
Skin Prick Test
In order to determine whether the patient is allergic to olive pollen, drop an olive pollen extract on his/her skin, then gently prick it with a needle and observe the skin's reaction.
Creative BioMart provides high-quality recombinant Olea europaea allergen proteins used for IVD, including ELISA, lateral flow assay, western blot, and other immunoassays.
High specificity and sensitivity. Our products exhibit greater specificity since they are meticulously designed and created to target known, specific allergen proteins.
High purity, no contamination with non-specific allergens.
Easy to scale up production. A large number of specific proteins can be obtained through process amplification, without being limited by the content of natural extracts and materials.
Higher safety and repeatability.
Our Outstanding Advantages
A comprehensive range of IVD products to meet the different needs of customers and provide customers with comprehensive scientific research support.
We can provide first-class services through a skilled technical team combined with advanced scientific research equipment and technology.
Pay attention to service quality, provide customers with timely and accurate IVD-related services, and ensure that customers can get the best scientific research experience.
In addition, Creative BioMart also offers a series of allergen proteins and protein-related services to provide customers with high-quality, low-cost active recombinant proteins to meet different needs and assist in preclinical drug development.
Creative BioMart specializes in the IVD field, offering a wide range of IVD proteins for both biological exploration and clinical research. Additionally, we provide highly personalized and top-tier protein services for IVD reagents, drug discovery, biotechnology research production, and other related fields. For more information about our exceptional products and services, please contact us.
Reference
García-Sánchez J, del Mar Trigo M, Recio M. (2019). Extraction and quantification of Ole e 1 from atmospheric air samples: An optimized protocol[J]. Chemosphere. 225: 490-496.
