The parasitic eukaryotic animal Plasmodium, which causes malaria, has a very specific host preference. In addition to being a serious human health risk, malaria is also an important issue related to public health. Plasmodium enters the human body through the saliva of the Anopheles mosquito, reproduces asexually in human liver cells, and then invades and destroys red blood cells. The development of Plasmodium in the human body is divided into extraerythrocytic and intraerythrocytic stages. Infected patients eventually develop clinical symptoms such as chills, trembling, and sweating.
Figure 1. Plasmodium Life Cycle. (Chahine Z, et al., 2022)
Main Steps of IVD for Plasmodium
Antibody testing. It mainly includes indirect fluorescent antibody (IFA), indirect hemagglutination assay (IHA), and enzyme-linked immunosorbent assay (ELISA).
Serological testing. Specific antigens are detected by utilizing radioimmunoassay, inhibition enzyme-linked immunosorbent assay, sandwich enzyme-linked immunosorbent assay, and rapid immunochromatographic test card (ICT).
Molecular biology technology. PCR and nucleic acid probes have higher detection rates for hypoprotozoaemia.
Etiological diagnosis. Blood samples are obtained from the patient's peripheral blood and made into two types of blood films, thick and thin, and then stained and examined under a microscope.
High purity and uniformity. The protein purity is above 90% and verified by SDS-PAGE.
High batch-to-batch consistency and low variability.
Completed biological functions and efficient activity.
Easy to store and transport, conducive to large-scale production and use of vaccines.
Outstanding success rate and fast development speed.
Our Outstanding Advantages
IVD proteins can be used to test for a variety of diseases and conditions, making them valuable tools for diagnosing and monitoring health.
Guarantee high performance, high reliability, and high consistency of protein quality, leading the industry.
A complete IVD protein platform can provide customized services to meet different scientific research needs.
High-quality service, high-level experiments, and reliable analysis.
In addition, Creative BioMart also offers a series of viral proteins and protein-related services to provide customers with high-quality, low-cost active recombinant proteins to meet different needs and assist in preclinical drug development.
Creative BioMart offers a series of highly efficient and reliable IVD proteins, providing strong support for medical research and preclinical diagnosis. At the same time, we provide more flexible and personalized protein services that are used in IVD reagents, drug development, biotechnology research and production, and other fields. Please contact us for answers if you are interested in our products or services.
Reference
Chahine Z, Le Roch K G. (2022). Decrypting the complexity of the human malaria parasite biology through systems biology approaches[J]. Frontiers in systems biology. 2: 940321.
Figure 1. Plasmodium Life Cycle. (Chahine Z, et al., 2022)
