Pet allergies refer to symptoms such as nasal itching, runny nose, asthma, and rashes caused by allergies to pet hair and dander. Cats and dogs are the most common allergenic pets and have become the third largest category of inhaled allergens after dust mites and pollen allergens. There are currently 7 major allergenic proteins in dogs that have been identified, among which Can f 1 and Can f 5 are the main allergenic protein components. In addition, the main allergenic protein in cat hair is Fel d 1, while Equ c 1 is the secreted protein that induces IgE-mediated allergic reactions in most patients allergic to horses.
Main Steps of IVD for Pet Allergy
Skin Test
It mainly includes intradermal tests and prick tests, which can detect the patient's sensitivity to allergens.
Serum-Specific IgE Testing
This method can detect the content of pet allergen-specific IgE, such as specific IgE antibodies against cat hair, dog hair, or other pet hair, dander, and other components.
Molecular Diagnostics
Modern molecular biology techniques are used to detect the gene expression of IgE antibodies that specifically bind to pet allergens in the human body to discover allergen-specific IgE and perform quantitative and qualitative detection.
Creative BioMart provides a diverse range of pet allergy-related recombinant allergen proteins used for IVD, including ELISA, lateral flow assay, western blot, and other immunoassays.
Wide range of applications. Used for the development of various immunotherapies and vaccines as well as the production and preparation of various diagnostic reagents.
High purity and specificity. Genetic engineering technology allows it to be produced without non-specific allergens.
High sensitivity. The molecular structure and biological activity of recombinant allergens are similar to natural allergens and can effectively stimulate immune responses in allergic patients.
Easy to scale up production.
Higher safety and repeatability.
Our Outstanding Advantages
The R&D team has rich experience and high-level technical capabilities and can provide you with continuously innovative products and services.
A wide range of in-vitro diagnostic (IVD) products are available to meet diverse customer needs and support scientific research.
Focus on service quality, provide customers with timely and accurate services, and ensure that customers can get the best scientific research experience.
In addition, Creative BioMart also offers a series of allergen proteins and protein-related services to provide customers with high-quality, low-cost active recombinant proteins to meet different needs and assist in preclinical drug development.
Creative BioMart can offer various highly efficient and reliable IVD proteins, providing strong support for medical research and preclinical diagnosis. At the same time, we provide more flexible and personalized protein services that are used in IVD reagents, drug development, biotechnology research and production, and other fields. Please contact us for answers if you are interested in our products or services.
Reference
Arbes Jr S J, Cohn R D, Yin M, et al. (2004). Dog allergen (Can f 1) and cat allergen (Fel d 1) in US homes: results from the National Survey of Lead and Allergens in Housing[J]. Journal of allergy and clinical immunology. 114(1): 111-117.
