Dermatophagoides farinae (Der f) is the main source of inhaled allergens and is highly related to the occurrence of allergic diseases. Der f allergens refer to the protein components of Der f, including their corpses, secretions, excretions, and eggs. When these substances are spread in the air and inhaled by the human body, they can cause allergic rhinitis, allergic asthma, urticaria, dermatitis, and a series of other symptoms. Currently, immunological detection methods such as ELISA are usually used to detect specific IgE antibodies against Der f 2 allergens in patients' serum to diagnose dust mite allergy in vitro.
Main Steps of IVD for Dermatophagoides farinae Allergy
Immunological Test
Methods mainly include ELISA, skin prick test, and western blot, among which ELISA is one of the most commonly used methods. During the IVD process, the allergen protein of Der f 2 is combined with the specific IgE antibody in the patient's serum for immunological testing to determine whether the patient has an immune response to the allergens of Der f, thereby helping to diagnose allergy.
Molecular Biology Test
The main methods are gene cloning, gene expression, and protein analysis, which can detect the genes and proteins of Der f to further confirm the allergens of Der f.
Creative BioMart provides high-quality recombinant allergen Der f 2 used for IVD, including ELISA, lateral flow assay, western blot, and other immunoassays.
Highlights of Our Products
High purity, no non-specific allergen contamination.
High specificity. The molecular structure and biological activity of recombinant allergens are similar to natural allergens and can effectively stimulate immune responses in allergic patients.
Easy to scale up production. A large number of specific proteins can be obtained through process amplification, without being limited by the content of natural extracts and materials.
Higher safety and repeatability.
Our Outstanding Advantages
Strong technical team, advanced scientific research equipment, and technology that can provide high-quality services.
A rich variety of IVD products to meet the different needs of customers and provide customers with comprehensive scientific research support.
Pay attention to service quality, provide customers with timely and accurate IVD-related services, and ensure that customers can get the best scientific research experience.
In addition, Creative BioMart also offers a series of allergen proteins and protein-related services to provide customers with high-quality, low-cost active recombinant proteins to meet different needs and assist in preclinical drug development.
Creative BioMart has a wide range of highly effective and reliable IVD proteins for use in medical research and preclinical diagnostics. We also offer custom protein services to meet the diverse needs of IVD reagents, drug discovery, biotechnology research, and other related sectors, providing flexible solutions to meet individual requirements. Please contact us for more information if you are interested in any of our products or services.
Reference
Johannessen B R, Skov L K, Kastrup J S, et al. (2005). Structure of the house dust mite allergen Der f 2: implications for function and molecular basis of IgE cross-reactivity[J]. FEBS letters. 579(5): 1208-1212.
