Drug abuse refers to the repeated and large-scale use of drugs with dependence properties in the form of self-administration for non-medical purposes. Long-term drug abuse can produce mental and physical dependence, leading to mental confusion and abnormal behavior. A technology known as in vitro diagnostics (IVD) is an important tool for monitoring drug abuse. By collecting individual biological samples such as urine, blood, and hair, it can be detected whether specific drugs are used, as well as the amount and frequency of use. This information is important for assessing the extent, type, and risk of drug abuse and for tracking and treating drug abusers.
The Role of IVD in Drug Abuse Monitoring
Determine whether an individual has used drugs by detecting drugs or their metabolites in biological samples.
Help monitoring agencies better understand the current status and trends of drug abuse.
Provide support for the development and implementation of drug abuse prevention and treatment policies.
IVD Methods for Drug Abuse
Immunoassay. The principle of binding specific antibodies to target drugs is used to detect drugs or their metabolites in biological samples.
Spectral analysis. The absorption and scattering effects of different substances on the spectrum are used to detect drugs or their metabolites in biological samples.
Chromatography. The difference in distribution coefficients of different substances between the stationary phase and the mobile phase is used to separate the target drug and its metabolites, and then detect the target drug and its metabolites.
Mass spectrometry. The target drug is ionized using an ion source, and then the target drug and its metabolites are separated and detected in a mass spectrometer.
Infrared spectroscopy. Detect drugs or their metabolites in biological samples using infrared spectroscopy.
Antibodies can be used to detect drug residues or to determine whether someone has been exposed to a drug. Currently, a variety of antibodies have been developed for different drugs of abuse, such as antibodies against sedative-hypnotics, opioids, amphetamines, cocaine, etc. Creative BioMart can provide customized IVD antibody services to assist in drug abuse monitoring.
Advantages of Our Services
Advanced technology platforms improve the efficiency and precision of antibody development to a certain extent.
Customized services. Provide personalized antibody services according to customer needs, including antigen screening, antibody optimization, drug efficacy evaluation, etc.
Strict quality control. There is a strict quality control system during the development process to ensure the accuracy and reliability of every link, thereby providing customers with high-quality products.
Creative BioMart provides high-quality IVD recombinant proteins for the preparation of IVD reagents such as kits, detection reagents, and calibrators. As a leading IVD expert, Creative BioMart has rich R&D experience and technology to provide important foundation and support for the development of the IVD field. To help research institutions better conduct various biological research, we can offer diverse IVD raw materials and customized services. If you are interested in our products or services, you can contact us for more details.
Reference
O'Brien C P. (2006). Drug addiction and drug abuse[J]. Goodman and Gilman's the pharmacological basis of therapeutics. 11: 607-627.
