Native Influenza B [B/Massachusetts/2/12] Viral Lysate
Specification
Related Products
| Cat#: |
INF-462 |
| Product Name: |
Native Influenza B [B/Massachusetts/2/12] Viral Lysate |
| Description: |
Influenza B (B/Massachusetts/2/12) viral lysate is an enveloped virus with a diameter of 80-120 nm, and contains a single-stranded, segmented, negative-sense RNA within a nucleocapsid. Influenza Virus is a Biosafety Level 2 organism. Viral inactivation of this product is verified for every lot of lysate by the absence of viral growth in validated tissue culture based infectivity assays. |
| Gene: |
IBV |
| Species: |
Influenza B [B/Massachusetts/2/12] |
| Synonyms: |
Influenza B [B/Massachusetts/2/12] Viral Lysate |
| Notes: |
This product is intended for research and manufacturing uses only. It is not a diagnostic device. The user assumes all responsibility for care, custody and control of the material, including its disposal, in accordance with all regulations. |
| Applications: |
Suitable for the development of immunoassays, Western blotting, dot blotting and other protein-based assays. |
| Background: |
The influenza B virus is the only species of virus in the genus Betainfluenzavirus within the family Orthomyxoviridae. Influenza B viruses have linear, negative-sense, single-stranded multipartite RNA genomes. The Influenza B virus capsid is enveloped and its virion comprises an envelope protein, matrix protein, nucleoprotein complex, a nucleocapsid, and polymerase complex. Influenza viruses are highly pleomorphic, with 500 or so surface projections of Hemagglutinin (HA) and Neuraminidase (NA). Unlike influenza A viruses, influenza B viruses are limited to infecting only humans and seals (Osterhaus et al., 2000) and can be divided into the two B/Yamagata/16/88-like and B/Victoria/2/87 lineages according to the antigenic properties of their Haemagglutinin surface proteins. The limited host range of influenza B viruses and their inability to genetically reassort is responsible for the lack of associated influenza pandemics in contrast with those caused by related influenza A viruses that mutate by both antigenic drift and shift. The variability of the type B viruses, however, is also characterised by other mechanisms such as insertion and deletion, as the influenza B lines show which have been co-circulating and stable for more than 20 years (Untergruppe, 2009). The Massachusetts/2/2012 strain of influenza B virus was first isolated in 2012 in the state of Massachusetts, USA (Influenza Research Database). |
For research use only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
