Native Cytomegalovirus Purified Antigen
Specification
Related Products
| Cat#: |
CYT-145 |
| Product Name: |
Native Cytomegalovirus Purified Antigen |
| Description: |
Cytomegalovirus purified antigen has been manufactured in response to the in-vitro diagnostics (IVD) industry's requirement for a cost effective antigen which can demonstrate a high affinity IgG and for IgM. This Cytomegalovirus (CMV) purified antigen when compared to standard lysates reduces the likelihood of cross-reactivity and minimizes lot to lot variation. The product can readily be scaled to meet the need for bulk volumes at significant discounts. CMV purified antigen is offered in a ready to use liquid format. |
| Gene: |
CMV |
| Species: |
Cytomegalovirus |
| Synonyms: |
CMV |
| Formulation: |
0.2% Triton X-100, 10mM Tris-HCl, 1mM EDTA and 100mM NaCl, pH7.8 |
| Concentration: |
Adjusted to 1 mg/mL by BCA assay |
| Purity: |
Purified by ultracentrifugation |
| Storage: |
Store frozen at less than -20 centigrade, preferably -80 centigrade. |
| Notes: |
This product is intended for research and manufacturing uses only. It is not a diagnostic device. The user assumes all responsibility for care, custody and control of the material, including its disposal, in accordance with all regulations. |
| Usage: |
Avoid freeze/thawing. Purified enveloped viruses can aggregate upon freeze/thawing, so homogenisation by vortexing or sonication is recommended before use. |
| Inactivation: |
Purified virus particles were lysed in 0.2% Triton X-100 in STE buffer. The lysate was tested by passage on permissive cells for 2 weeks yielding no CPE. |
| Background: |
Cytomegalovirus (CMV, or human betaherpesvirus 5) is a human-specific double-stranded DNA virus, belonging to the Herpesviridae family. CMV is ubiquitous and CMV infection is globally widespread. The virus is transmitted through direct contact with infected bodily fluids, or though contact with virus-infected transplant and transfusion material. Presently, CMV infection is mostly controlled in immune compromised patients by available antiviral drugs, yet it continues to maintain its role as one of the most dangerous infectious agents for an unborn infant. Primary infection is consistently associated with the presence of a virus specific IgM antibody response. Use of Cytomegalovirus purified antigen will aid in improving serology based assays for early detection. |
For research or industrial raw materials, not for personal medical use!
